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Journal of Bone and Joint Surgery, 1959;41:349-362.
© 1959 by The Journal of Bone and Joint Surgery, Inc

Ewing's Sarcoma and Reticulum-Cell Sarcoma of Bone

With Special Reference to the Histochemical Demonstration of Glycogen as an Aid to Differential Diagnosis

Fritz Schajowicz M.D.1

1 Laboratory of Pathology of the Department of Orthopaedic Surgery and Traumatology, Italian Hospital, and Faculty of Medicine, Buenos Aires

1. Primary reticulum-cell sarcoma of bone is an entity which may be differentiated from Ewing's sarcoma, histologically, with the aid of ordinary and special staining methods. The differentiation is important because of the different prognosis of each tumor.

2. The histochemical demonstration of glycogen in tumor cells of Ewing's sarcoma and its absence in reticulum-cell sarcoma of bone proved to be an easy, efficient method of differential diagnosis.

3. Appropriate fixatives and stains must be used to achieve uniform results.


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