This Article
Right arrow Full Text (PDF)
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowReprints and Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stinchfield, F. E.
Right arrow Articles by Samilson, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stinchfield, F. E.
Right arrow Articles by Samilson, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Technorati  
What's this?
Journal of Bone and Joint Surgery, 1956;38:270-282.
© 1956 by The Journal of Bone and Joint Surgery, Inc

The Effect of Anticoagulant Therapy on Bone Repair

Frank E. Stinchfield M.D.1, Balu Sankaran M.B., F.R.C.S.C.1, and Robert Samilson M.D.1

1 New York, N. Y.

1. Twenty-six control and twenty-six experimental animals were studied.

2. In the control rabbits bony union occurred in four weeks; in the control dogs it occurred in six weeks.

3. When the animals received anticoagulants in the preoperative period, they showed evidence of delayed union.

See Table in the PDF file

4. When the anticoagulants were given in the immediate postoperative period, fibrous union resulted.

5. When heparin or dicumarol were given one week after the operation, delayed union occurred.

6. It is not the authors' intention to conclude from this study that non-union will necessarily occur in a patient who has received anticoagulant therapy; they feel, however, that the possibility of its occurring must be considered.

7. The findings of this experimental study are of interest and may have a clinical significance and application. It is hoped that these findings will stimulate further interest in the general field of fibrous tissue behavior.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 JBJSHome page
J. G. Wright, S. Yandow, S. Donaldson, L. Marley, and on Behalf of The Simple Bone Cyst Trial Group
A Randomized Clinical Trial Comparing Intralesional Bone Marrow and Steroid Injections for Simple Bone Cysts
J. Bone Joint Surg. Am., April 1, 2008; 90(4): 722 - 730.
[Abstract] [Full Text] [PDF]