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Journal of Bone and Joint Surgery, 1950;32:323-337.
© 1950 by The Journal of Bone and Joint Surgery, Inc

FIBROUS DYSPLASIA OF BONE

LYLE W. RUSSELL M.D.1 and FREMONT A. CHANDLER M.D.1

1 Department of Orthopaedic Surgery, The University of Illinois Research and Educational Hospitals, Chicago

1. Fibrous dysplasia of bone includes monostotic lesions, polyostotic lesions, and Albright's syndrome.

2. The basic morphology of all three groups includes replacement of cortical and cancellous bone and marrow by fibrous connective tissue, containing varying amounts of imperfect cancellous bone.

3. The etiology and pathogenesis of fibrous dysplasia of bone are still obscure.

4. The diagnosis may sometimes be made on the basis of clinical and roentgenographic examinations, but often a biopsy is necessary to differentiate from other conditions.

5. Treatment consists in reduction and immobilization of pathological fractures, correction of deformities, and surgical excision of painful lesions, whenever possible.


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