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Journal of Bone and Joint Surgery, 1949;31:793-814.
© 1949 by The Journal of Bone and Joint Surgery, Inc

Clinical Evaluation of the Merthiolate Bone Bank. A Preliminary Report

Fred C. Reynolds M.D.1 and David R. Oliver M.D.1

1 St. Louis, Missouri

1. The process of fixation and replacement of both autogenous and known dead homogenous bone grafts is accomplished in an identical manner, experimentally and clinically.

2. The merthiolate bone bank offers a simple, inexpensive, and aseptic method of preserving homogeneous bone.

3. Merthiolate-preserved bone is well tolerated in the tissues, and early results obtained with grafts from the merthiolate bone bank compare favorably with autogenous grafts under similar circumstances.

See image in the PDF file

4. No sensitivity to merthiolate has been encountered in any case.

5. Experimentally and clinically, the early phases of healing are somewhat slower with homogenous grafts than with autogenous grafts. Therefore, it is important that immobilization be continued over a longer period of time.


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