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Journal of Bone and Joint Surgery, 1949;31:413-416.
© 1949 by The Journal of Bone and Joint Surgery, Inc

FIBROSARCOMA OF THE TIBIA FOLLOWING CHRONIC OSTEOMYELITIS

Report of a Case

Jack D. Kirshbaum M.D., F.A.C.P.1

1 Department of Pathology, Kern General Hospital, Bakersfield

Sarcoma following a chronic inflammatory process in such regions as the kidney, liver, or breast is well known; and there is no reason why a neoplasm, such as fibrosarcoma, may not develop in bone which is the site of osteomyelitis. However, sarcoma in bone has rarely been preceded by osteomyelitis. The case described supports the theory of chronic inflammation as a predisposing factor in the formation of malignant neoplasms.

The tumor in this case probably had its origin in the fibrous bone marrow of the tibia.


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