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Journal of Bone and Joint Surgery, 1947;29:509-514.
© 1947 by The Journal of Bone and Joint Surgery, Inc

CHONDRODYSTROPHIA CALCIFICANS CONGENITA

Report of Two Cases

THEODORE H. VINKE M.D.1 and F. PAUL DUFFY M.D.1

1 Orthopaedic Department of the College of Medicine, University of Cincinnati, and the Orthopaedic Service of the Cincinnati Children's Hospital

Case reports of a two-month-old white girl and of her brother, aged two years and eleven months, are presented because of the roentgenographic findings of calcareous deposits within the cartilage of the joints and in many epiphyses. The girl was admitted for orthopaedic correction of talipes calcaneovalgus deformity, and the calcareous deposits were discovered during routine roentgenography. All laboratory studies failed to disclose the cause for the deposits. The boy had scattered irregular calcareous deposits within the cartilage about the tarsal bones, but these were less numerous than those found in his sister.

After study of the British and American literature, nine similar case reports of infants were found. Several patients had congenital heart lesions or cataracts. Neither of these conditions was found in our patients. Several of the case reports mention stippled epiphyses in older children4,10,12,13,14. These cases are not similar to ours, because the authors report stippling of the epiphyses without the presence of diffuse calcareous opacities within the cartilage. We contend that our cases represent an entity separate and distinct from that occurring in older children.


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