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Journal of Bone and Joint Surgery, 1941;23:516-520.
© 1941 by The Journal of Bone and Joint Surgery, Inc

THE USE OF SULFATHIAZOLE IN THE TREATMENT OF SUBACUTE AND CHRONIC OSTEOMYELITIS

FRANK D. DICKSON M.D.1, REX L. DIVELEY M.D.1, and RICHARD KIENE M.D.1

1 KANSAS CITY, MISSOURI

1. A series of twenty-two foci of subacute and chronic osteomyelitis is reported in which the treatment employed was the administration of sulfathiazole by mouth, thorough débridement of the focus, and the introduction of sulfathiazole powder into the wound. In 82 per cent. of the cases in this series, there was healing by primary intention with an average healing period of twenty-three days following surgery.

2. This is a comparatively small series of cases, and no attempt can be made from it to arrive at a final conclusion as to the value of the method proposed. However, the results have been sufficiently satisfactory, both in regard to the type of healing and the healing period, to suggest that the method should be given a thorough trial.


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