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Journal of Bone and Joint Surgery, 1940;22:324-326.
© 1940 by The Journal of Bone and Joint Surgery, Inc

RELATION BETWEEN REDUCED ASCORBIC-ACID LEVELS OF THE BLOOD PLASMA AND RHEUMATOID ARTHRITIS

RICHARD H. JACQUES M.D.1

1 COLUMBUS, OHIO

The ascorbic-acid level of the blood plasma in active cases of rheumatoid arthritis is regularly low.

With the use of adequate amounts of ascorbic acid, orally and parenterally, it is readily possible to raise the plasma level to within normal limits.

There is no marked clinical response, even though the plasma level has been returned to normal.

The low ascorbic-acid content of the blood plasma present in active cases of rheumatoid arthritis is probably a reflection of the general state of malnutrition and has no etiological significance.


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