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Journal of Bone and Joint Surgery, 1940;22:185-199.
© 1940 by The Journal of Bone and Joint Surgery, Inc

GONORRHOEAL ARTHRITIS: A PROPOSED PLAN OF SULFANILAMIDE THERAPY

ORMOND S. CULP M.D.1 and MILTON C. COBEY M.D.1

1 James Buchanan Brady Urological Institute and Department of Orthopaedics, Johns Hopkins Hospital

In gonorrhoeal arthritis, sulfanilamide promises to be the most efficacious form of therapy, but in another paper 7 we have shown that intravenous mercurochrome also may be of great value.

A group of fifty patients, treated with sulfanilamide on the Hospital wards and in the Out-Patient Department, have been analyzed, and 82 per cent. have been found to be cured or markedly improved.

The best results have been obtained in the acute cases and in those instances where the blood sulfanilamide has reached at least eight milligrams per 100 cubic centimeters.

A practical plan for routine treatment of all cases has been proposed, including minor forms of supplementary therapy which will be especially valuable in the small number of cases in which the response to chemotherapy alone is unavoidably poor.


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