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Journal of Bone and Joint Surgery, 1936;18:69-79.
© 1936 by The Journal of Bone and Joint Surgery, Inc

THE INFLUENCE OF ROENTGEN IRRADIATION ON THE RATE OF HEALING OF FRACTURES AND THE PHOSPHATASE ACTIVITY OF THE CALLUS OF ADULT BONE

EUGENE M. REGEN M.D.1 and WALTER E. WILKINS Ph.D.2

1 The Department of Surgery, Vanderbilt University School of Medicine, Nashville
2 The Department of Biochemistry, Vanderbilt University School of Medicine, Nashville

Moderate doses of x-rays given previous to the production of fracture in adult rabbit bone result in marked delay of union and inhibition of the rise in phosphatase activity that normally accompanies the healing of a fracture.


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