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Journal of Bone and Joint Surgery, 1931;13:68-74.
© 1931 by The Journal of Bone and Joint Surgery, Inc

THE INFLUENCE OF ALTERATIONS IN THE CIRCULATION ON THE REPAIR OF BONE

HERMAN E. PEARSE JR. M.D.1 and JOHN J. MORTON M.D.1

1 The Department of Surgery, the University of Rochester, School of Medicine and Dentistry

Previous work has shown that blocking the deep veins to produce venous stasis at the site of healing results in an increased callus formation and accelerated bone repair. This is a useful procedure in treating delayed union of fractures.

Obstruction of the lesser saphenous vein has no influence on the healing of the fibula.

Blocking the arterial circulation by ligation of the main trunk has no effect because of the rapid development of collateral circulation. When the main artery and its branches are removed, there is delay in bone repair but healing eventually takes place.

Removal of the lumbar sympathetic trunk and ganglia makes very little change in the process of bone repair in the extremity.


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